Wound care is interest of many people. Healing a wound is priority to the body. The complex system of wound healing presents an adaptive advantage that ensures the survival of the organism. In this regard when injured, the wound is an effective parasite removing from the body what it needs. The aim of this book is to raise awareness in our colleagues who read the book by addressing hard-to-heal atypical wound cases that have been non healing misdiagnosed or undiagnosed in the wound care related outpatient and inpatient clinics. This book presents thirteen non healing wound cases with atypical diagnosis. These cases are usually misdiagnosed, overlooked by wound care physicians and nurses. Delaying the patient-tailored appropriate treatment may cause loss of limb and would be fatal. Thelossof alimbcan have a considerable psychological impact.